Ketosis, whether induced by fasting or by following a ketogenic diet, is associated with a reduction in dietary glucose. The body has elegant mechanisms that allow it to utilize non-carbohydrate substrates to generate glucose. Gluconeogenesis is a metabolic pathway in which the liver produces glucose from non-carbohydrate substrates including glucogenic amino acids (from protein) and glycerol (from lipids). In athletes, skeletal muscle is constantly being remodeled and may serve as a source of glucogenic amino acids.

In this clip, Dr. Dominic D’Agostino describes how gluconeogenesis fills an important role during ketosis to maintain a basal level of glucose.
This clip was taken from the first FoundMyFitness interview with Dominic D’Agostino found at https://www.youtube.com/watch?v=lQ7pSXIWHrI

Original episode published on Apr 9, 2016